You have probably read stories that say that coffee is bad for you, and others that say that coffee is good for you. Well the truth is that it depends partially on your genes. A number of studies have shown that people with one variation of the CYP1A2 gene don’t break down caffeine as well as others. They are called “slow metabolizers”. People with another variant in this gene break down caffeine easily and are called “fast metabolizers” Slow metabolizers tend to have a higher risk of heart problems if they drink coffee and fast metabolizers have a lower risk of heart problems if they drink coffee. Want to find out if you should be drinking coffee? Sign up to get early access to the test we are developing.
Cornelis MC et al. . “Coffee, CYP1A2 genotype, and risk of myocardial infarction.” JAMA. 2006 295(10):1135-41.
El-Sohemy A et al. Coffee, CYP1A2 genotype and risk of myocardial infarction. Genes Nutr. 2007 Oct;2(1):155-6.